Mining the genomes of exceptional responders

被引：33

作者：

Chang, David K. ^{[1
,2
,3
,4
,5
]}

Grimmond, Sean M. ^{[1
,6
]}

Evans, T. R. Jeffry ^{[1
]}

Biankin, Andrew V. ^{[1
,2
,3
,4
,5
]}

机构：

[1] Univ Glasgow, Inst Canc Sci, Wolfson Wohl Canc Res Ctr, Glasgow G61 1BD, Lanark, Scotland

[2] Garvan Inst Med Res, Canc Div, Kinghorn Canc Ctr, Sydney, NSW 2010, Australia

[3] Univ New S Wales, Fac Med, St Vincents Clin Sch, Darlinghurst, NSW 2010, Australia

[4] Bankstown Hosp, Dept Surg, Sydney, NSW 2200, Australia

[5] Univ New S Wales, Fac Med, South Western Sydney Clin Sch, Liverpool, NSW 2170, Australia

[6] Univ Queensland, Inst Mol Biosci, Queensland Ctr Med Genom, Brisbane, Qld 4067, Australia

来源：

NATURE REVIEWS CANCER | 2014年 / 14卷 / 05期

关键词：

D O I：

10.1038/nrc3723

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The National Cancer Institute of the United States recently announced a major new initiative in understanding the genomes or, more broadly, the molecular phenotypes of exceptional responders. What can we expect to learn from exceptional responders? What are the potential benefits, and how do we approach studying them?

引用

页码：291 / 292

页数：2

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