Targeting and beyond: New roles for old signal sequences

被引:15
作者
Hegde, RS [1 ]
机构
[1] NICHD, Cell Biol & Metab Branch, NIH, Bethesda, MD 20892 USA
关键词
D O I
10.1016/S1097-2765(02)00692-5
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Signal sequences, once considered degenerate hydrophobic elements whose sole task is to target proteins to the secretory pathway, are increasingly being recognized as playing roles beyond targeting. Recent work is beginning to shed light on some of the ways the cell decodes and exploits additional functions encoded within signal sequences.
引用
收藏
页码:697 / 698
页数:2
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