Rapid response to infliximab in severe pustular psoriasis, von Zumbusch type

被引：54

作者：

Newland, MR ^{[1
]}

Weinstein, A ^{[1
]}

Kerdel, F ^{[1
]}

机构：

[1] Univ Miami, Dept Dermatol, Miami, FL 33152 USA

来源：

INTERNATIONAL JOURNAL OF DERMATOLOGY | 2002年 / 41卷 / 07期

关键词：

D O I：

10.1046/j.1365-4362.2002.01543.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Tumor necrosis factor-alpha (TNF-alpha) is a chemokine secreted by T cells which is thought to play a critical role in the pathophysiology of psoriasis. The monoclonal antibody, infliximab, complexes with TNF-alpha, rendering it inactive. A recent clinical trial has reported the clinical benefit and safety of infliximab in moderate to severe plaque psoriasis. We report a case of rapid response and clinical benefit using infliximab in severe pustular psoriasis of von Zumbusch.

引用

页码：449 / 452

页数：4

共 6 条

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