How NOD-ing off leads to Crohn disease

被引：15

作者：

O'Neill, LAJ ^{[1
]}

机构：

[1] Univ Dublin Trinity Coll, Dept Biochem, Dublin 2, Ireland

来源：

NATURE IMMUNOLOGY | 2004年 / 5卷 / 08期

关键词：

D O I：

10.1038/ni0804-776

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Many patients with Crohn disease, an inflammatory bowel disorder, carry mutations in NOD2. The finding that NOD2 normally dampens Toll-like receptor 2-mediated inflammation may explain this association.

引用

页码：776 / 778

页数：4

共 9 条

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