Design of a sequence-specific DNA bisintercalator

被引：46

作者：

Fechter, EJ ^{[1
]}

Olenyuk, B ^{[1
]}

Dervan, PB ^{[1
]}

机构：

[1] CALTECH, Div Chem & Chem Engn, Pasadena, CA 91125 USA

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2004年 / 43卷 / 27期

关键词：

conjugation; DNA recognition; intercalation; polyamides;

D O I：

10.1002/anie.200454231

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Programmable bisintercalators: Symmetric synthetic DNA bisintercalators (see picture) based on the H-pin polyamide motif afford high affinity and programmable sequence specificity.

引用

页码：3591 / 3594

页数：4

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