LPA in neural cell development

被引：53

作者：

Fukushima, N ^{[1
]}

机构：

[1] Hokkaido Univ, Grad Sch Med, Dept Biochem, Kita Ku, Sapporo, Hokkaido 0608638, Japan

来源：

JOURNAL OF CELLULAR BIOCHEMISTRY | 2004年 / 92卷 / 05期

关键词：

LPA; neuron; glia; development;

D O I：

10.1002/jcb.20093

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Lysophosphatidic acid (LPA) elicits diverse cellular responses through cell surface LPA receptors in nervous system-derived cells and cell lines. The developing nervous system is one of the major loci for LPA receptor expression. Recent studies have also revealed that metabolic pathways of LPA are present in the nervous system. A growing body of literature Suggests a crucial role for LPA in neuronal development processes, including neurogenesis, neuronal migration, neuritogenesis, and myelination. (C) 2004 Wiley-Liss, Inc.

引用

页码：993 / 1003

页数：11

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