Glutamic acid, twenty years later

被引：67

作者：

Garattini, S ^{[1
]}

机构：

[1] Mario Negri Inst Pharmacol Res, I-20157 Milan, Italy

来源：

JOURNAL OF NUTRITION | 2000年 / 130卷 / 04期

关键词：

glutamic acid; monosodium glutamate; metabolism; central nervous system; neurodegeneration; N-methyl-D-aspartate; alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate; metabotropic receptors; glutamate transporters;

D O I：

10.1093/jn/130.4.901S

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 [营养与食品卫生学];

摘要：

This review examines progress in understanding the physiologic functions of glutamic acid in the body since the first symposium on glutamic acid physiology and biochemistry was held at the Mario Negri Institute in Milan in 1978. The topics reviewed, although not exhaustive, include the metabolism of glutamic acid, umami taste, the role of glutamic acid as a neurotransmitter, glutamate safety and the development of new drugs resulting from the knowledge of the neurodegeneration induced by high doses of glutamic acid.

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页码：901S / 909S

页数：9

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