Can drugs be designed?

被引：26

作者：

Hubbard, RE

机构：

[1] Department of Chemistry, University of York, Heslington

来源：

CURRENT OPINION IN BIOTECHNOLOGY | 1997年 / 8卷 / 06期

关键词：

D O I：

10.1016/S0958-1669(97)80122-X

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Many examples are now emerging of the successful use of rational, structure-based methods in drug discovery. Of particular note is the development of imaginative NMR-based methods for rapid routes to ligand design. Our understanding of the chemistry underlying protein-ligand interactions, however, remains relatively poor and a major limitation in our ability to truly design drugs. (C) Current Biology Ltd ISSN 0958-1669.

引用

收藏

页码：696 / 700

页数：5

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