Novel sequences propel familiar folds

被引：103

作者：

Jawad, Z ^{[1
]}

Paoli, M ^{[1
]}

机构：

[1] Univ Cambridge, Dept Biochem, Cambridge CB2 1QW, England

来源：

STRUCTURE | 2002年 / 10卷 / 04期

基金：

英国生物技术与生命科学研究理事会;

关键词：

D O I：

10.1016/S0969-2126(02)00750-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Recent structure determinations have made new additions to a set of strikingly different sequences that give rise to the same topology. Proteins with a P propeller fold are characterized by extreme sequence diversity despite the similarity in their three-dimensional structures. Several fold predictions, based in part on sequence repeats thought to match modular P sheets, have been proved correct.

引用

页码：447 / 454

页数：8

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