Osteosarcoma of the pelvis

被引:35
作者
Donati, D
Giacomini, S
Gozzi, E
Ferrari, S
Sangiorgi, L
Tienghi, A
DeGroot, H
Bertoni, F
Bacchini, P
Bacci, G
Mercuri, M
机构
[1] Ist Ortoped Rizzoli, Dept Musculoskeletal Oncol & Orthopaed Surg, I-40136 Bologna, Italy
[2] Ist Ortoped Rizzoli, Dept Musculoskeletal Oncol & Chemotherapy, I-40136 Bologna, Italy
[3] Ist Ortoped Rizzoli, Dept Musculoskeletal Oncol & Basic Res, I-40136 Bologna, Italy
[4] City Hosp Ravenna, Chemotherapy Unit, Ravenna, Italy
[5] Univ Massachusetts, Sch Med, Worcester, MA 01655 USA
[6] Ist Ortoped Rizzoli, Dept Musculoskeletal Oncol & Pathol, I-40136 Bologna, Italy
来源
EJSO | 2004年 / 30卷 / 03期
关键词
osteosarcoma; bone neoplasms; pelvic surgery; chemotherapy; tumour recurrence; margins;
D O I
10.1016/j.ejso.2003.12.004
中图分类号
R73 [肿瘤学];
学科分类号
100214 [肿瘤学];
摘要
Aims. To describe the outcomes of a large number of patients with pelvic osteosarcoma, and to define the guidelines for appropriate treatment. Methods. We reviewed 60 consecutive patients with primary pelvic high-grade osteosarcoma. The tumour involved the whole hemipelvis in 15 cases, white the most common Location was the iliac wing in 29 cases (48.3%): 25 of these adjacent to or passing the sacroiliac joint. Results. Thirty patients underwent surgery; there were 16 hindquarter amputations and 14 internal hemipelvectomies. ALL the patients who presented with metastasis died of their disease. In 18 cases wide margins were achieved, however, eight patients experienced local recurrence. Of the series, only eight patients are still alive. Conclusion. The use of intense chemotherapy and surgical. wide margin, hardly seems to achieve Local. control, however, tumour necrosis was correlated with positive prognosis. When internal hemipelvectomy it is not safe enough, amputation must be considered, particularly for cases with sacrifice of the sciatic nerve roots or for older patients where a shorter surgical procedure can be less risky. (C) 2004 Published by Elsevier Ltd.
引用
收藏
页码:332 / 340
页数:9
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