Effects of hydroxyethyl starch on blood coagulation profile

被引：17

作者：

Türkan, H ^{[1
]}

Ural, AU

Beyan, C

Yalçin, A

机构：

[1] Golcuk Naval Hosp, Dept Anaesthesiol, TR-41650 Golcuk Izmit, Turkey

[2] Gulhane Mil Med Acad, Dept Hematol, Ankara, Turkey

来源：

EUROPEAN JOURNAL OF ANAESTHESIOLOGY | 1999年 / 16卷 / 03期

关键词：

hydroxyethyl starch; coagulation;

D O I：

10.1046/j.1365-2346.1999.00407.x

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

The effects of hydroxyethyl starch on blood coagulation were investigated in 20 patients undergoing surgery to determine whether its use places recipients at risk of haemorrhage or thrombosis. The partial thromboplastin times are significantly prolonged; factor VIII activities and fibrinogen levels are decreased. After infusion of hydroxyethyl starch, no significant differences were detected in platelet count or prothrombin time. A decreased platelet aggregation was also found after the infusion of hydroxyethyl starch. According to our results, hydroxyethyl starch can cause haemorrhagic problems in patients when administered as a colloidal volume-expanding agent.

引用

页码：156 / 159

页数：4

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