Evolution of CPV-2 and implicance for antigenic/genetic characterization

被引：59

作者：

Martella, Vito ^{[1
]}

Decaro, Nicola ^{[1
]}

Buonavoglia, Canio ^{[1
]}

机构：

[1] Univ Bari, Fac Vet Med, Dept Anim Hlth & Wellbeing, I-70010 Bari, Italy

来源：

VIRUS GENES | 2006年 / 33卷 / 01期

关键词：

canine parvovirus; CPV-2; characterization; antigenic variant; evolution;

D O I：

10.1007/s11262-005-0034-8

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

A few amino acid differences in the viral protein VP2 account for important antigenic and biological changes among feline parvovirus (FPV), canine parvovirus (CPV-2) and CPV-2 variants 2a and 2b. Several pieces of evidence suggest that CPV-2 is still evolving as additional amino acid changes occurred within the main antigenic regions of CPV-2 capsid, altering the antigenic profile of the virus and stressing the need for implementing the diagnostic assays.

引用

页码：11 / 13

页数：3

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