NOS knockouts and neuroprotection

被引：35

作者：

Grünewald, T ^{[1
]}

Beal, MF ^{[1
]}

机构：

[1] Cornell Univ, New York Presbyterian Hosp, Dept Neurol, New York, NY 10021 USA

来源：

NATURE MEDICINE | 1999年 / 5卷 / 12期

关键词：

D O I：

10.1038/70918

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Neuronal nitric oxide synthase (nNOS) is known to be involved in the dopaminergic neurodegeneration that occurs in the MPTP model of Parkinson disease. Recent studies indicate that different isoforms of NOS may act synergistically to cause neuronal injury in Parkinson disease and other neurodegenerative diseases (pages 1403-1409).

引用

页码：1354 / 1355

页数：2

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