Acute disseminated demyelination due to primary human herpesvirus-6 infection

被引：51

作者：

Kamei, A ^{[1
]}

Ichinohe, S ^{[1
]}

Onuma, R ^{[1
]}

Hiraga, S ^{[1
]}

Fujiwara, T ^{[1
]}

机构：

[1] IWATE PREFECTURAL KAMAISHI HOSP,KAMAISHI,IWATE,JAPAN

来源：

EUROPEAN JOURNAL OF PEDIATRICS | 1997年 / 156卷 / 09期

关键词：

human herpesvirus-6; exanthem subitum; encephalopathy; acute demyelination;

D O I：

10.1007/s004310050695

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

A previously healthy 19-month-old boy developed acute encephalopathy, thrombocytopenia and hepatic dysfunction. Human herpesvirus-6 (HHV-6) DNA was found in his CSF during the acute stage of the disease by means of the polymerase chain reaction. T2-weighted MRI revealed high signal intensity in the left thalamus and left parieto-occipital deep white matter. The myelin basic protein concentration in the CSF was elevated suggesting acute demyelination. The patient is now 2.5 years old and has no sequelae. Conclusion Since clinical course and neuroimaging after HHV-6 infection are similar to those in acute disseminated encephalomyelitis, clinicians must pay attention to primary HHV-6 infection in patients under 2 years old with white matter lesions.

引用

收藏

页码：709 / 712

页数：4

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