Treatment of childhood migraine attacks with oral zolmitriptan and ibuprofen

被引：65

作者：

Evers, S.

Rahmann, A.

Kraemer, C.

Kurlemann, G.

Debus, O.

Husstedt, I. W.

Frese, A.

机构：

[1] Univ Munster, Dept Neurol, Munster, Germany

[2] Univ Munster, Dept Neuropaediat, Munster, Germany

来源：

NEUROLOGY | 2006年 / 67卷 / 03期

关键词：

D O I：

10.1212/01.wnl.0000231138.18629.d5

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The authors conducted a double-blind, placebo-controlled, crossover study to investigate the efficacy of oral zolmitriptan in the treatment of migraine in children and adolescents. Patients ( n = 32) received placebo, zolmitriptan 2.5 mg, and ibuprofen 200 to 400 mg to treat three consecutive migraine attacks. Pain relief rates after 2 hours were 28% for placebo, 62% for zolmitriptan, and 69% for ibuprofen ( p < 0.05). Both drugs are well tolerated with only mild side effects.

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页码：497 / 499

页数：3

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