Relative and absolute configurations of ganefromycin α

被引：10

作者：

Andersson, T ^{[1
]}

Berova, N ^{[1
]}

Nakanishi, K ^{[1
]}

Carter, GT ^{[1
]}

机构：

[1] Columbia Univ, Dept Chem, New York, NY 10027 USA

来源：

ORGANIC LETTERS | 2000年 / 2卷 / 07期

关键词：

D O I：

10.1021/ol005598u

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] The full structure of ganefromycin alpha has been determined. The relative configurations were determined from (3)J(H,H) coupling constants and NOE data, while the absolute configurations in moieties A and a were determined separately by difference CD of their acylate derivatives, which showed typical exciton couplets, The configurations of the stereogenic centers in ganefromycin alpha are 8S, 9S, 11R, 12S, 13S, 21S, 22R, 23R, 24R, and 26S.

引用

页码：919 / 922

页数：4

共 8 条

[1] CHEMISTRY AND STRUCTURE OF GANEFROMYCIN [J].