Synthesis of BF2 chelates of tetraarylazadipyrromethenes and evidence for their photodynamic therapeutic behaviour

被引：351

作者：

Killoran, J

Allen, L

Gallagher, JF

Gallagher, WM

O'Shea, DF ^{[1
]}

机构：

[1] Univ Coll Dublin, Dept Chem, Conway Inst, Ctr Synth & Chem Biol, Dublin 4, Ireland

[2] Univ Coll Dublin, Dept Pharmacol, Conway Inst, Dublin 4, Ireland

[3] Dublin City Univ, Sch Chem Sci, Dublin 9, Ireland

来源：

CHEMICAL COMMUNICATIONS | 2002年 / 17期

关键词：

D O I：

10.1039/b204317c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The synthesis, spectroscopic characteristics and in vitro cellular uptake properties of a new class of therapeutic window photosensitiser, namely the BF2 chelates of 3,5-diaryl-1H- pyrrol-2-yl-3,5-diarylpyrrol-2-ylidene amines (tetraarylazadipyrromethenes), are described with the aim of developing a novel class of photodynamic therapeutic agents.

引用

页码：1862 / 1863

页数：2

共 10 条

[1] Metal complexes as photo- and radiosensitizers
Ali, H
van Lier, JE
[J]. CHEMICAL REVIEWS, 1999, 99 (09) : 2379 - 2450
[2] PHOTOSENSITIZERS OF THE PORPHYRIN AND PHTHALOCYANINE SERIES FOR PHOTODYNAMIC THERAPY
BONNETT, R
[J]. CHEMICAL SOCIETY REVIEWS, 1995, 24 (01) : 19 - 33
[3] Photodynamic therapy
Dougherty, TJ
Gomer, CJ
Henderson, BW
Jori, G
Kessel, D
Korbelik, M
Moan, J
Peng, Q
[J]. JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 1998, 90 (12): : 889 - 905
[4] BETA-CYCLOYLPROPIONITRILES .2. CONVERSION INTO BIS-2-(5-CYCLYLPYRROLE)AZAMETHIN SALTS
KNOTT, EB
[J]. JOURNAL OF THE CHEMICAL SOCIETY, 1947, (SEP): : 1196 - 1201
[5] Basic principles of photodynamic therapy
MacDonald, IJ
Dougherty, TJ
[J]. JOURNAL OF PORPHYRINS AND PHTHALOCYANINES, 2001, 5 (02) : 105 - 129
[6] Octaalkynyltetra[6,7]quinoxalinoporphyrazines: a new class of photosensitisers with potential for photodynamic therapy
Mitzel, F
FitzGerald, S
Beeby, A
Faust, R
[J]. CHEMICAL COMMUNICATIONS, 2001, (24) : 2596 - 2597
[7] The role of apoptosis in response to photodynamic therapy: what, where, why, and how
Oleinick, NL
Morris, RL
Belichenko, T
[J]. PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES, 2002, 1 (01) : 1 - 21
[8] 2 4-Diarylpyrroles Part II Methines
Rogers, MAT
[J]. JOURNAL OF THE CHEMICAL SOCIETY, 1943, : 596 - 597
[9] 2-PHOTON EXCITATION OF ALKYL-SUBSTITUTED MAGNESIUM PHTHALOCYANINE - RADICAL FORMATION VIA HIGHER EXCITED-STATES
STIEL, H
TEUCHNER, K
PAUL, A
FREYER, W
LEUPOLD, D
[J]. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 1994, 80 (1-3) : 289 - 298
[10] WAINWRIGHT M, 1996, CHEM SOC REV, P351

← 1 →