Bifidogenic effect and stimulation of short chain fatty acid production in human faecal slurry cultures by oligosaccharides derived from lactose and lactulose

被引：53

作者：

Cardelle-Cobas, Alejandra ^{[1
]}

Fernandez, Maria ^{[2
]}

Salazar, Nuria ^{[2
]}

Martinez-Villaluenga, Cristina ^{[1
]}

Villamiel, Mar ^{[1
]}

Ruas-Madiedo, Patricia ^{[2
]}

de los Reyes-Gavilan, Clara G. ^{[2
]}

机构：

[1] CSIC, Inst Fermentac Ind, E-28006 Madrid, Spain

[2] CSIC, Inst Prod Lacteos Asturias, Villaviciosa 33300, Asturias, Spain

来源：

JOURNAL OF DAIRY RESEARCH | 2009年 / 76卷 / 03期

关键词：

Oligosaccharides; bifidogenic effect; short chain fatty acids; lactose; lactulose; HUMAN GUT MICROFLORA; ULTRA SP-L; BETA-GALACTOSIDASE; IN-VITRO; KLUYVEROMYCES-LACTIS; ENZYMATIC PRODUCTION; INTESTINAL BACTERIA; RESISTANT STARCH; HEALTHY-SUBJECTS; DOUBLE-BLIND;

D O I：

10.1017/S0022029909004063

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

090502 [动物营养与饲料科学];

摘要：

Bifidogenic effect and stimulation of short chain fatty acid (SCFA) production by fractions of oligosaccharides with a DP >= 3 and Gal beta(1-6) linkages synthesised from lactose or lactulose by Pectinex Ultra SP-L and Lactozym 3000 L HP G were evaluated in human faecal slurries. Results were compared with those obtained for the commercial oligosaccharide mixture Vivinal (R)-GOS. Quantitative real-time PCR showed that all galacto-oligosaccharide (GOS) fractions stimulated slightly higher bifidobacteria growth than lactose, lactulose and Vivinal (R)-GOS. GOS fractions promoted the production of total SCFA and acetic acid in a similar way to Vivinal (R)-GOS and more than glucose, lactose and lactulose. In conclusion, oligosaccharides derived from lactose and lactulose may represent a suitable alternative to lactulose for the design of new functional food ingredients.

引用

页码：317 / 325

页数：9

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