Siphonazole, an unusual metabolite from Herpetosiphon sp.

被引：59

作者：

Nett, Markus

Erol, Oezlem

Kehraus, Stefan

Koeck, Matthias

Krick, Anja

Eguereva, Ekaterina

Neu, Edith

Koenig, Gabriele M.

机构：

[1] Univ Bonn, Inst Pharmaceut Biol, D-53115 Bonn, Germany

[2] Alfred Wegener Inst Polar & Marine Res, D-27570 Bremerhaven, Germany

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2006年 / 45卷 / 23期

关键词：

biosynthesis; herpetosiphon; natural products; siphonazole; structure elucidation;

D O I：

10.1002/anie.200504525

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Deep and complex: The first representative (see picture) of a new structural class has been isolated from a deep-rooted filamentous bacterium of the genus Herpetosiphon. Feeding with 13C and 15N-labeled precursors showed the complex biosynthesis to involve shikimate, the polyketide, and the amino acid metabolism. (Figure Presented) © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：3863 / 3867

页数：5

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