Linkage analysis of Alzheimer disease with psychosis

被引：48

作者：

Bacanu, SA

Devlin, B

Chowdari, KV

DeKosky, ST

Nimgaonkar, VL

Sweet, RA

机构：

[1] Univ Pittsburgh, Med Ctr, Dept Psychiat, Sch Med, Pittsburgh, PA 15213 USA

[2] Univ Pittsburgh, Dept Neurol, Sch Med, Pittsburgh, PA 15213 USA

来源：

NEUROLOGY | 2002年 / 59卷 / 01期

关键词：

D O I：

10.1212/WNL.59.1.118

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Although a portion of risk for late-onset AD (LOAD) is attributable to APOE, the search for other loci is ongoing. The authors hypothesize that psychotic symptoms with LOAD (LOAD+P) identify a potentially more etiologically homogeneous form of AD. Linkage analysis of families with LOAD+P identified one significant and several suggestive novel linkage signals, which bolsters the conjecture of greater etiologic homogeneity.

引用

页码：118 / 120

页数：3

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