Shaping the dynamic mitochondrial network

被引：102

作者：

Lackner, Laura L. ^{[1
]}

机构：

[1] Northwestern Univ, Dept Mol Biosci, Evanston, IL 60208 USA

来源：

BMC BIOLOGY | 2014年 / 12卷

关键词：

INNER-MEMBRANE-FUSION; CLASS-V-MYOSIN; ENDOPLASMIC-RETICULUM; MITOFUSIN; CONFORMATIONAL-CHANGES; AXONAL MITOCHONDRIA; CRYSTAL-STRUCTURE; QUALITY-CONTROL; MOTOR-PROTEIN; FISSION;

D O I：

10.1186/1741-7007-12-35

中图分类号：

Q [生物科学];

学科分类号：

090105 [作物生产系统与生态工程];

摘要：

In a majority of cell types, mitochondria form highly dynamic, tubular networks. Maintaining the shape of this complex network is critical for both mitochondrial and cellular function and involves the activities of mitochondrial division, fusion, motility, and tethering. Recent studies have advanced our understanding of the molecular mechanisms underlying these conserved activities and their integration with cellular needs.

引用

页数：10

共 116 条

[1]

Membrane Tethering and Nucleotide-dependent Conformational Changes Drive Mitochondrial Genome Maintenance (Mgm1) Protein-mediated Membrane Fusion [J].

Abutbul-Ionita, Inbal ;

Rujiviphat, Jarungjit ;

Nir, Iftach ;

McQuibban, G. Angus ;

Danino, Dganit .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2012, 287 (44) :36634-36638

[2]

Association between the endoplasmic reticulum and mitochondria of yeast facilitates interorganelle transport of phospholipids through membrane contact [J].

Achleitner, G ;

Gaigg, B ;

Krasser, A ;

Kainersdorfer, E ;

Kohlwein, SD ;

Perktold, A ;

Zellnig, G ;

Daum, G .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1999, 264 (02) :545-553

[3]

The class V myosin motor protein, Myo2, plays a major role in mitochondrial motility in Saccharomyces cerevisiae [J].

Altmann, Katrin ;

Frank, Martina ;

Neumann, Daniel ;

Jakobs, Stefan ;

Westermann, Benedikt .

JOURNAL OF CELL BIOLOGY, 2008, 181 (01) :119-130

[4]

The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission [J].

Anand, Ruchika ;

Wai, Timothy ;

Baker, Michael J. ;

Kladt, Nikolay ;

Schauss, Astrid C. ;

Rugarli, Elena ;

Langer, Thomas .

JOURNAL OF CELL BIOLOGY, 2014, 204 (06) :919-929

[5]

Two Deubiquitylases Act on Mitofusin and Regulate Mitochondrial Fusion along Independent Pathways [J].

Anton, Fabian ;

Dittmar, Gunnar ;

Langer, Thomas ;

Escobar-Henriques, Mafalda .

MOLECULAR CELL, 2013, 49 (03) :487-498

[6]

Upregulated function of mitochondria-associated ER membranes in Alzheimer disease [J].

Area-Gomez, Estela ;

Castillo, Maria Del Carmen Lara ;

Tambini, Marc D. ;

Guardia-Laguarta, Cristina ;

de Groof, Ad J. C. ;

Madra, Moneek ;

Ikenouchi, Junichi ;

Umeda, Masato ;

Bird, Thomas D. ;

Sturley, Stephen L. ;

Schon, Eric A. .

EMBO JOURNAL, 2012, 31 (21) :4106-4123

[7]

The mitochondrial fission factor dynamin-related protein 1 modulates T-cell receptor signalling at the immune synapse [J].

Baixauli, Francesc ;

Martin-Cofreces, Noa B. ;

Morlino, Giulia ;

Carrasco, Yolanda R. ;

Calabia-Linares, Carmen ;

Veiga, Esteban ;

Serrador, Juan M. ;

Sanchez-Madrid, Francisco .

EMBO JOURNAL, 2011, 30 (07) :1238-1250

[8]

Stress-induced OMA1 activation and autocatalytic turnover regulate OPA1-dependent mitochondrial dynamics [J].

Baker, Michael J. ;

Lampe, Philipp A. ;

Stojanovski, Diana ;

Korwitz, Anne ;

Anand, Ruchika ;

Tatsuta, Takashi ;

Langer, Thomas .

EMBO JOURNAL, 2014, 33 (06) :578-593

[9]

OPA1 disease alleles causing dominant optic atrophy have defects in cardiolipin-stimulated GTP hydrolysis and membrane tubulation [J].

Ban, Tadato ;

Heymann, Juergen A. W. ;

Song, Zhiyin ;

Hinshaw, Jenny E. ;

Chan, David C. .

HUMAN MOLECULAR GENETICS, 2010, 19 (11) :2113-2122

[10]

Dynamics of nucleoid structure regulated by mitochondrial fission contributes to cristae reformation and release of cytochrome c [J].

Ban-Ishihara, Reiko ;

Ishihara, Takaya ;

Sasaki, Narie ;

Mihara, Katsuyoshi ;

Ishihara, Naotada .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2013, 110 (29) :11863-11868

← 1 2 3 4 5 6 7 8 9 10 →