Bacterial invasion: A new strategy to dominate cytoskeleton plasticity

被引：24

作者：

Cossart, P ^{[1
]}

机构：

[1] Inst Pasteur, INSERM, Unite Interact Bacteries Cellules, U604, F-75015 Paris, France

来源：

DEVELOPMENTAL CELL | 2004年 / 6卷 / 03期

关键词：

D O I：

10.1016/S1534-5807(04)00072-3

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Some bacteria[ pathogens enter mammalian cells by injecting, directly into the host cytosol, proteins that trigger cytoskeletal rearrangements necessary for internalization. In the February 27 issue of Molecular Cell, McGhie et al. identify mechanisms by which the Salmonella protein SipA interferes with ADF/cofilin and gelsolin function. Thus Salmonella not only triggers actin polymerization but also counteracts the major F-actin destabilizing proteins.

引用

页码：314 / 315

页数：2

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