Mannich-type reactions of aldehydes, amines, and ketones in a colloidal dispersion system created by a Bronsted acid-surfactant-combined catalyst in water

被引：226

作者：

Manabe, K ^{[1
]}

Kobayashi, S ^{[1
]}

机构：

[1] Univ Tokyo, Japan Sci & Technol Corp, JST, Grad Sch Pharmaceut Sci,CREST,Bunkyo Ku, Tokyo 1130033, Japan

来源：

ORGANIC LETTERS | 1999年 / 1卷 / 12期

关键词：

D O I：

10.1021/ol991113u

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] Three-component Mannich-type reactions of aldehydes, amines, and ketones were efficiently catalyzed by dodecylbenzenesulfonic acid at ambient temperature in water to give various beta-amino ketones in good yields. The same reactions proceeded sluggishly in organic solvents.

引用

页码：1965 / 1967

页数：3

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