Magnetic core-shell Fe3O4@SiO2/MWCNT nanocomposite modified carbon paste electrode for amplified electrochemical sensing of uric acid

被引：137

作者：

Arvand, Majid ^{[1
]}

Hassannezhad, Morassa ^{[1
]}

机构：

[1] Univ Guilan, Fac Sci, Dept Chem, Rasht, Iran

来源：

MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS | 2014年 / 36卷

关键词：

Nanocomposite; Magnetic core-shell Fe3O4@SiO2 nanopartides; Multi-walled carbon nanotubes; Uric acid; PULSE VOLTAMMETRIC DETERMINATION; ASCORBIC-ACID; PHARMACEUTICAL FORMULATIONS; NANOPARTICLES; NANOTUBES; PARACETAMOL; DOPAMINE; POLYANILINE; BIOSENSORS; SERUM;

D O I：

10.1016/j.msec.2013.12.014

中图分类号：

TB3 [工程材料学]; R318.08 [生物材料学];

学科分类号：

082905 [生物质能源与材料]; 100103 [病原生物学];

摘要：

A new type of nanocomposite based on multi-walled carbon nanotubes decorated with magnetic core-shell Fe3O4@SiO2 nanoparticles (Fe3O4@SiO2/MWCNTs) was prepared and used to fabricate a modified carbon paste electrode (CPE). The nanocomposite was characterized by transmission electron microscopy (TEM), scanning electron microscopy (SEM), energy dispersive X-ray spectroscopy (EDX) and Fourier transform infrared spectroscopy (FT-IR) techniques. Electrochemical behavior of uric acid (UA) was investigated on Fe3O4@SiO2/MWCNTs-CPE by cyclic voltammetry (CV) and square wave voltammetry (SWV) in phosphate buffer solution (pH 6.0). Under the optimized conditions, the peak currents increased linearly with the concentration of UA in the range from 0.60 to 100.0 mu M, with a detection limit of 0.13 mu M. The proposed sensor was successfully applied for the determination of UA in biological fluids. (C) 2013 Elsevier B.V. All rights reserved.

引用

页码：160 / 167

页数：8

共 46 条

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Simultaneous voltammetric determination of tyrosine and paracetamol using a carbon nanotube-graphene nanosheet nanocomposite modified electrode in human blood serum and pharmaceuticals [J].