Studies on antidiarrhoeal activity of Punica granatum seed extract in rats

被引：78

作者：

Das, AK

Mandal, SC

Banerjee, SK

Sinha, S

Das, J

Saha, BP

Pal, M ^{[1
]}

机构：

[1] Jadavpur Univ, Fac Engn & Technol, Dept Pharmaceut Technol, Calcutta 700032, W Bengal, India

[2] Univ Coll Med, Dept Pharmacol, Dr BC Roy PG Inst Basic Med Sci, Calcutta 700032, W Bengal, India

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 1999年 / 68卷 / 1-3期

关键词：

Punica granatum; seed extract; antidiarrhoeal;

D O I：

10.1016/S0378-8741(99)00102-6

中图分类号：

Q94 [植物学];

学科分类号：

071001 [植物学];

摘要：

Methanol extract of Punica granatum seed was evaluated for antidiarrhoeal activity against different experimental models of diarrhoea in rats. P. granatum seed extract treated animals showed significant inhibitory activity against castrol-oil induced diarrhoea and PGE(2) induced enteropooling in rats. The extract also showed a significant reduction in gastro-intestinal motility in charcoal meal test in rats. The results obtained established the efficacy of P. granatum seed extract as an antidiarrhoeal agent. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.

引用

页码：205 / 208

页数：4

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