The origin of prokaryotic C2H2 zinc finger regulators

被引:60
作者
Bouhouche, N
Syvanen, M
Kado, CI
机构
[1] Univ Calif Davis, Davis Crown Gall Grp, Davis, CA 95616 USA
[2] Univ Calif Davis, Sch Med, Dept Med Microbiol & Immunol, Davis, CA 95616 USA
关键词
D O I
10.1016/S0966-842X(99)01679-0
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
C2H2 zinc finger bearing proteins are a large superfamily of nucleic acid binding proteins, which constitute a major subset of eukaryotic transcription factors. Although originally thought to occur only in eukaryotes, a novel C2H2 zinc finger transcription factor, Ros, which regulates both prokaryotic and eukaryotic promoters has been found in bacteria. Phylogenically, Ros is distantly related to eukaryotic zinc finger regulators.
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页码:77 / 81
页数:5
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