No Association Between Common POLG1 Variants and Sporadic Idiopathic Parkinson's Disease

被引:20
作者
Hudson, Gavin [1 ]
Tiangyou, Watcharee [1 ]
Stutt, Andrea [2 ]
Eccles, Martin [3 ]
Robinson, Louise [3 ]
Burn, David J. [2 ]
Chinnery, Patrick F. [1 ,2 ]
机构
[1] Newcastle Univ, Mitochondrial Res Grp, Newcastle Upon Tyne NE1 7RU, Tyne & Wear, England
[2] Newcastle Univ, Inst Hlth & Aging, Newcastle Upon Tyne NE1 7RU, Tyne & Wear, England
[3] Newcastle Univ, Inst Hlth & Soc, Newcastle Upon Tyne NE1 7RU, Tyne & Wear, England
基金
英国惠康基金;
关键词
POLYMERASE; MUTATION;
D O I
10.1002/mds.22310
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
引用
收藏
页码:1092 / 1094
页数:3
相关论文
共 7 条
[1]   Mitochondrial DNA polymerase W748S mutation:: A common cause of autosomal recessive ataxia with ancient European origin [J].
Hakonen, AH ;
Heiskanen, S ;
Juvonen, V ;
Lappalainen, I ;
Luoma, PT ;
Rantamäki, M ;
Van Goethem, G ;
Löfgren, A ;
Hackman, P ;
Paetau, A ;
Kaakkola, S ;
Majamaa, K ;
Varilo, T ;
Udd, B ;
Kääiäinen, H ;
Bindoff, LA ;
Suomalainen, A .
AMERICAN JOURNAL OF HUMAN GENETICS, 2005, 77 (03) :430-441
[2]   MANAGING TURBULENT HEARTS - A BALINESE FORMULA FOR LIVING - WIKAN,U [J].
HUGHESFREELAND, F .
BULLETIN OF THE SCHOOL OF ORIENTAL AND AFRICAN STUDIES-UNIVERSITY OF LONDON, 1992, 55 :184-185
[3]   Parkinsonism, premature menopause, and mitochondrial DNA polymerase γ mutations:: clinical and molecular genetic study [J].
Luoma, P ;
Melberg, A ;
Rinne, JO ;
Kaukonen, JA ;
Nupponen, NN ;
Chalmers, RM ;
Oldfors, A ;
Rautakorpi, I ;
Peltonen, L ;
Majamaa, K ;
Somer, H ;
Suomalainen, A .
LANCET, 2004, 364 (9437) :875-882
[4]   Mitochondrial DNA polymerase gamma variants in idiopathic sporadic Parkinson disease [J].
Luoma, P. T. ;
Eerola, J. ;
Ahola, S. ;
Hakonen, A. H. ;
Hellstroem, O. ;
Kivistoe, K. T. ;
Tienari, P. J. ;
Suomalainen, A. .
NEUROLOGY, 2007, 69 (11) :1152-1159
[5]   A novel polymerase γ mutation in a family with ophthalmoplegia, neuropathy, and Parkinsonism [J].
Mancuso, M ;
Filosto, M ;
Oh, SJ ;
DiMauro, S .
ARCHIVES OF NEUROLOGY, 2004, 61 (11) :1777-1779
[6]   Analysis of the trinucleotide CAG repeat from the human mitochondrial DNA polymerase gene in healthy and diseased individuals [J].
Rovio, A ;
Tiranti, V ;
Bednarz, AL ;
Suomalainen, A ;
Spelbrink, JN ;
Lecrenier, N ;
Melberg, A ;
Zeviani, M ;
Poulton, J ;
Foury, F ;
Jacobs, HT .
EUROPEAN JOURNAL OF HUMAN GENETICS, 1999, 7 (02) :140-146
[7]   Cross sectional prevalence survey of idiopathic Parkinson's disease and parkinsonism in London [J].
Schrag, A ;
Ben-Shlomo, Y ;
Quinn, NP .
BRITISH MEDICAL JOURNAL, 2000, 321 (7252) :21-+