Drug-Induced Liver Injury - Types and Phenotypes

被引：415

作者：

Hoofnagle, Jay H. ^{[1
]}

Bjornsson, Einar S. ^{[2
,3
]}

机构：

[1] NIDDK, Liver Dis Res Branch, Div Digest Dis & Nutr, NIH, Bethesda, MD 20892 USA

[2] Natl Univ Hosp Iceland, Dept Internal Med, Reykjavik, Iceland

[3] Univ Iceland, Fac Med, Reykjavik, Iceland

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2019年 / 381卷 / 03期

关键词：

SINUSOIDAL OBSTRUCTION SYNDROME; GREEN TEA EXTRACT; AUTOIMMUNE HEPATITIS; CELL TRANSPLANTATION; CAUSALITY ASSESSMENT; LACTIC-ACIDOSIS; FEATURES; HEPATOTOXICITY; OUTCOMES; FAILURE;

D O I：

10.1056/NEJMra1816149

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

The liver has a range of responses to drug-induced injury, with a number of phenotypes. In addition, idiosyncratic reactions may occur as a consequence of both direct drug action and indirect drug effects. Antibiotics are the most common cause of drug-induced liver injury.

引用

页码：264 / 273

页数：10

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