Clinical evaluation of glimepiride versus glyburide in NIDDM in a double-blind comparative study

被引：87

作者：

Dills, DG ^{[1
]}

Schneider, J ^{[1
]}

Aronoff, SL ^{[1
]}

Azorr, MA ^{[1
]}

Brunner, D ^{[1
]}

Cefalu, WT ^{[1
]}

Cohen, AJ ^{[1
]}

Cyrus, J ^{[1
]}

Freedman, Z ^{[1
]}

Haag, BL ^{[1
]}

Hamilton, BP ^{[1
]}

Littlejohn, TW ^{[1
]}

Lucas, CP ^{[1
]}

Matlock, JS ^{[1
]}

McGill, JB ^{[1
]}

Miller, SS ^{[1
]}

Nikolai, T ^{[1
]}

Ogilvie, JT ^{[1
]}

Podlecki, DA ^{[1
]}

Ricaurte, M ^{[1
]}

Roudebush, CP ^{[1
]}

Singh, SP ^{[1
]}

Smulovitz, J ^{[1
]}

Soler, NG ^{[1
]}

Stone, J ^{[1
]}

Stonesifer, LD ^{[1
]}

Tucker, WS ^{[1
]}

Wallum, BJ ^{[1
]}

White, J ^{[1
]}

Whittier, FC ^{[1
]}

Zieve, FJ ^{[1
]}

机构：

[1] HOECHST MARION ROUSSEL PHARMACEUT INC,CLIN RES,BRIDGEWATER,NJ

来源：

HORMONE AND METABOLIC RESEARCH | 1996年 / 28卷 / 09期

关键词：

glimepiride glyburide; non-insulin dependent diabetes mellitus; sulfonylurea; double-blind study;

D O I：

10.1055/s-2007-979831

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We report-on the results of a one-year, multicenter, randomized, double-blind, parallel-group titration study of the new sulfonylurea agent, glimepiride, versus use of non-micronized glyburide to treat 577 patients with non-insulin dependent diabetes mellitus (NIDDM). Similar decreases in both fasting plasma glucose and HbA1C were found using glimepiride and glyburide. There was a lower incidence of hypoglycemia with glimepiride than glyburide.

引用

页码：426 / 429

页数：4

共 5 条

[1]

[Anonymous], 1995, BMJ, V310, P83

[2]

DRAGER E, 1995, DIABETES RES CLIN S, V28, pS139

[3]

MULLER G, 1995, DIABETES RES CLIN S, V28, pS114

[4] CLINICAL-EVALUATION OF GLIMEPIRIDE (HOE490) IN NIDDM, INCLUDING A DOUBLE-BLIND COMPARATIVE-STUDY VERSUS GLICLAZIDE [J].

TSUMURA, K .

DIABETES RESEARCH AND CLINICAL PRACTICE, 1995, 28 :S147-S149

[5] United Kingdom prospective diabetes study 17: A 9-year update of a randomized, controlled trial on the effect of improved metabolic control on complications in non-insulin-dependent diabetes mellitus [J].

Turner, R ;

Cull, C ;

Holman, R .

ANNALS OF INTERNAL MEDICINE, 1996, 124 (01) :136-145

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