Ropinirole in Gilles de la Tourette syndrome

被引:38
作者
Anca, MH
Giladi, N
Korczyn, AD [1 ]
机构
[1] Tel Aviv Univ, Sackler Fac Med, Dept Neurol, Sieratzki Chair Neurol, IL-69978 Ramat Aviv, Israel
[2] Tel Aviv Univ, Tel Aviv Med Ctr, Dept Neurol, IL-69978 Ramat Aviv, Israel
关键词
D O I
10.1212/01.WNL.0000123111.00324.BF
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The effects of treatment with ropinirole (0.25 to 0.5 mg bid) were examined using an open-label design for 8 weeks in 15 subjects with Gilles de la Tourette syndrome (GdlT). All patients completed the study, and most showed an improvement in their tics during treatment. Low-dose ropinirole may improve the motor features in GdlT, but further controlled studies are necessary.
引用
收藏
页码:1626 / 1627
页数:2
相关论文
共 11 条
  • [1] Black KJ, 2000, MOVEMENT DISORD, V15, P1194, DOI 10.1002/1531-8257(200011)15:6<1194::AID-MDS1019>3.0.CO
  • [2] 2-H
  • [3] Comparison of the functional potencies of ropinirole and other dopamine receptor agonists at human D2(long), D3 and D4.4 receptors expressed in Chinese hamster ovary cells
    Coldwell, MC
    Boyfield, I
    Brown, T
    Hagen, JJ
    Middlemiss, DN
    [J]. BRITISH JOURNAL OF PHARMACOLOGY, 1999, 127 (07) : 1696 - 1702
  • [4] FEINBERG M, 1979, ARCH GEN PSYCHIAT, V36, P979
  • [5] An international perspective on Tourette syndrome: selected findings from 3500 individuals in 22 countries
    Freeman, RD
    Fast, DG
    Burd, L
    Kerbeshian, J
    Robertson, MM
    Sandor, P
    [J]. DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY, 2000, 42 (07) : 436 - 447
  • [6] FRIEDHOFF AJ, 1982, GILLES TOURETTE SYND, P133
  • [7] Tic reduction with pergolide in a randomized controlled trial in children
    Gilbert, DL
    Dure, L
    Sethuraman, G
    Raab, D
    Lane, J
    Sallee, FR
    [J]. NEUROLOGY, 2003, 60 (04) : 606 - 611
  • [8] TALIPEXOLE AND ADULT GILLES-DE-LA-TOURETTES SYNDROME - DOUBLE-BLIND, PLACEBO-CONTROLLED CLINICAL-TRIAL
    GOETZ, CG
    STEBBINS, GT
    THELEN, JA
    [J]. MOVEMENT DISORDERS, 1994, 9 (03) : 315 - 317
  • [9] KORCZYN AD, 1993, HDB TOURETTES SYNDRO, P481
  • [10] A five-year study of the incidence of dyskinesia in patients with early Parkinson's disease who were treated with ropinirole or levodopa
    Rascol, O
    Brooks, DJ
    Korczyn, AD
    De Deyn, PP
    Clarke, CE
    Lang, AE
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2000, 342 (20) : 1484 - 1491