Enantioselective recognition of amino acid by differential pulse voltammetry in molecularly imprinted monolayers assembled on Au electrodes

被引：18

作者：

Huan, SY ^{[1
]}

Shen, GL ^{[1
]}

Yu, RQ ^{[1
]}

机构：

[1] Hunan Univ, State Key Lab Chemo Biosensing & Chemometr, Hunan 410082, Peoples R China

来源：

ELECTROANALYSIS | 2004年 / 16卷 / 12期

关键词：

entantioselectivity; differential pulse voltammetry; molecular imprinting; monolayer; L-Serine;

D O I：

10.1002/elan.200302879

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

An electrochemical sensor based on L-cysteine SAM imprinted by L-serine has been developed for the detection of L-serine. The sensor shows some entantioselectivity toward L-serine and a stable response establishes within 5 min. The peak current intensity of potassium ferricyanide quantified by differential pulse voltammetry (DPV) decreased linearly with increasing L-serine concentration from 10 to 100 muM with a gradient of 20.91 nA muM(-1). The detection limit was 4.32 muM. The coefficient of enantiometric selectivity of the molecularly imprinted SAM was about 3.0. Compounds with similar structure as serine caused much less response.

引用

页码：1019 / 1023

页数：5

共 27 条

[1] STUDIES ON GUEST SELECTIVE MOLECULAR RECOGNITION ON AN OCTADECYL SILYLATED SILICON SURFACE USING ELLIPSOMETRY [J].

ANDERSSON, LI ;

MANDENIUS, CF ;

MOSBACH, K .

TETRAHEDRON LETTERS, 1988, 29 (42) :5437-5440

[2] FORMATION OF MONOLAYER FILMS BY THE SPONTANEOUS ASSEMBLY OF ORGANIC THIOLS FROM SOLUTION ONTO GOLD [J].

BAIN, CD ;

TROUGHTON, EB ;

TAO, YT ;

EVALL, J ;

WHITESIDES, GM ;

NUZZO, RG .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1989, 111 (01) :321-335

[3] Templated SAMs for metal ion recognition [J].

Colonna, B ;

Echegoyen, L .

CHEMICAL COMMUNICATIONS, 2001, (12) :1104-1105

[4] Molecularly imprinted sensor layers for the detection of polycyclic aromatic hydrocarbons in water [J].

Dickert, FL ;

Tortschanoff, M ;

Bulst, WE ;

Fischerauer, G .

ANALYTICAL CHEMISTRY, 1999, 71 (20) :4559-4563

[5]

Hage DS, 1999, ANAL CHEM, V71, p294R

[6] Imprinted polymer-based enantioselective acoustic sensor using a quartz crystal microbalance [J].

Haupt, K ;

Noworyta, K ;

Kutner, W .

ANALYTICAL COMMUNICATIONS, 1999, 36 (11-12) :391-393

[7] Molecularly imprinted polymers and their use in biomimetic sensors [J].

Haupt, K ;

Mosbach, K .

CHEMICAL REVIEWS, 2000, 100 (07) :2495-2504

[8] Electrooxidative coupling of a toluidine blue O terminated self-assembled monolayer studied by electrochemistry and surface enhanced Raman spectroscopy [J].

Ju, HX ;

Xiao, Y ;

Lu, XJ ;

Chen, HY .

JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 2002, 518 (02) :123-130

[9] COMPETITIVE AMPEROMETRIC MORPHINE SENSOR-BASED ON AN AGAROSE IMMOBILIZED MOLECULARLY IMPRINTED POLYMER [J].

KRIZ, D ;

MOSBACH, K .

ANALYTICA CHIMICA ACTA, 1995, 300 (1-3) :71-75

[10] INTRODUCING BIOMIMETIC SENSORS BASED ON MOLECULARLY IMPRINTED POLYMERS AS RECOGNITION ELEMENTS [J].

KRIZ, D ;

RAMSTROM, O ;

SVENSSON, A ;

MOSBACH, K .

ANALYTICAL CHEMISTRY, 1995, 67 (13) :2142-2144

← 1 2 3 →