A green route to β-amino alcohols via the uncatalyzed aminolysis of 1,2-epoxides by alkyl- and arylamines

被引：63

作者：

Bonollo, Simona ^{[1
]}

Fringuelli, Francesco ^{[1
]}

Pizzo, Ferdinando ^{[1
]}

Vaccaro, Luigi ^{[1
]}

机构：

[1] Univ Perugia, Dipartimento Chim, CEMIN, I-06123 Perugia, Italy

来源：

GREEN CHEMISTRY | 2006年 / 8卷 / 11期

关键词：

D O I：

10.1039/b607620c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Under mildly basic and pH-controlled aqueous conditions the aminolysis of 1,2-epoxides 1a-g by alkyl- and arylamines 2a-k is generally highly regioselective giving the corresponding beta-amino alcohols in satisfactory to excellent yields.

引用

页码：960 / 964

页数：5

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