Adventures of a pore-forming toxin at the target cell surface

被引：113

作者：

Abrami, L ^{[1
]}

Fivaz, M ^{[1
]}

van der Goot, FG ^{[1
]}

机构：

[1] Univ Geneva, Dept Biochem, CH-1211 Geneva 4, Switzerland

来源：

TRENDS IN MICROBIOLOGY | 2000年 / 8卷 / 04期

关键词：

D O I：

10.1016/S0966-842X(00)01722-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The past three years have shed light on how the pore-forming toxin aerolysin binds to its target cell and then hijacks cellular devices to promote its own polymerization and pore formation. This selective permeabilization of the plasma membrane has unexpected intracellular consequences that might explain the importance of aerolysin in Aeromonas pathogenicity.

引用

页码：168 / 172

页数：5

共 31 条

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