Can trastuzumab be effective against tumors with low HER2/Neu (ErbB2) receptors?

被引：23

作者：

Arteaga, Carlos L. ^{[1
]}

机构：

[1] Vanderbilt Univ, Sch Med, Dept Med, Nashville, TN 37212 USA

[2] Vanderbilt Univ, Sch Med, Dept Canc Biol,Breast Canc Res Program, Vanderbilt Ingram Comprehens Canc Ctr, Nashville, TN 37212 USA

来源：

JOURNAL OF CLINICAL ONCOLOGY | 2006年 / 24卷 / 23期

关键词：

D O I：

10.1200/JCO.2006.06.5268

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：3722 / 3725

页数：4

共 44 条

[1] Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth [J].

Agus, DB ;

Akita, RW ;

Fox, WD ;

Lewis, GD ;

Higgins, B ;

Pisacane, PI ;

Lofgren, JA ;

Tindell, C ;

Evans, DP ;

Maiese, K ;

Scher, HI ;

Sliwkowski, MX .

CANCER CELL, 2002, 2 (02) :127-137

[2]

ALIMANDI M, 1995, ONCOGENE, V10, P1813

[3]

Atlas E, 2003, MOL CANCER RES, V1, P165

[4] c-erbB-3 protein expression in ductal carcinoma in situ of the breast [J].

Bobrow, LG ;

Millis, RR ;

Happerfield, LC ;

Gullick, WJ .

EUROPEAN JOURNAL OF CANCER, 1997, 33 (11) :1846-1850

[5] Increased HER2 gene copy number is associated with response to gefitinib therapy in epidermal growth factor receptor-positive non-small-cell lung cancer patients [J].

Cappuzzo, F ;

Varella-Garcia, M ;

Shigematsu, H ;

Domenichini, I ;

Bartolini, S ;

Ceresoli, GL ;

Rossi, E ;

Ludovini, V ;

Gregorc, V ;

Toschi, L ;

Franklin, WA ;

Crino, L ;

Gazdar, AF ;

Bunn, RA ;

Hirsch, FR .

JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (22) :5007-5018

[6] Structure of the extracellular region of HER2 alone and in complex with the Herceptin Fab [J].

Cho, HS ;

Mason, K ;

Ramyar, KX ;

Stanley, AM ;

Gabelli, SB ;

Denney, DW ;

Leahy, DJ .

NATURE, 2003, 421 (6924) :756-760

[7] Relationship of epidermal growth factor receptor expression to ErbB-2 signaling activity and prognosis in breast cancer patients [J].

DiGiovanna, MP ;

Stern, DF ;

Edgerton, SM ;

Whalen, SG ;

Moore, D ;

Thor, AD .

JOURNAL OF CLINICAL ONCOLOGY, 2005, 23 (06) :1152-1160

[8] EFFICIENT COUPLING WITH PHOSPHATIDYLINOSITOL 3-KINASE, BUT NOT PHOSPHOLIPASE C-GAMMA OR GTPASE-ACTIVATING PROTEIN, DISTINGUISHES ERBB-3 SIGNALING FROM THAT OF OTHER ERBB EGFR FAMILY MEMBERS [J].

FEDI, P ;

PIERCE, JH ;

DIFIORE, PP ;

KRAUS, MH .

MOLECULAR AND CELLULAR BIOLOGY, 1994, 14 (01) :492-500

[9] Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex [J].

Franklin, MC ;

Carey, KD ;

Vajdos, FF ;

Leahy, DJ ;

de Vos, AM ;

Sliwkowski, MX .

CANCER CELL, 2004, 5 (04) :317-328

[10] C-ERBB-3 AND C-ERBB-2 PROTEIN EXPRESSION IN NODE-NEGATIVE BREAST-CARCINOMA - AN IMMUNOCYTOCHEMICAL STUDY [J].

GASPARINI, G ;

GULLICK, WJ ;

MALUTA, S ;

DALLAPALMA, P ;

CAFFO, O ;

LEONARDI, E ;

BORACCHI, P ;

POZZA, F ;

LEMOINE, NR ;

BEVILACQUA, P .

EUROPEAN JOURNAL OF CANCER, 1994, 30A (01) :16-22

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