Cytoskeletal and adhesion proteins as tumor suppressors

被引：168

作者：

BenZeev, A

机构：

[1] Department of Molecular Cell Biology, Weizmann Institute of Science

来源：

CURRENT OPINION IN CELL BIOLOGY | 1997年 / 9卷 / 01期

关键词：

D O I：

10.1016/S0955-0674(97)80158-5

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

In the past year, significant progress has been made in the attempt to understand the molecular mechanisms underlying signaling that is induced by cell-cell and cell-extracellular-matrix adhesion and that involves the cytoskeleton. In particular, molecules of the cytoplasmic plaques of cell-cell junctions have been shown to complex with transcription factors and to translocate into the nucleus. In addition, such junctional plaque proteins have been shown to act as effective suppressors of tumorigenesis.

引用

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页码：99 / 108

页数：10

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