Pathology of US Porcine Epidemic Diarrhea Virus Strain PC21A in Gnotobiotic Pigs

被引：190

作者：

Jung, Kwonil ^{[1
]}

Wang, Qiuhong ^{[1
]}

Scheuer, Kelly A. ^{[1
]}

Lu, Zhongyan ^{[1
]}

Zhang, Yan ^{[2
]}

Saif, Linda J. ^{[1
]}

机构：

[1] Ohio State Univ, Wooster, OH 44691 USA

[2] Ohio Dept Agr, Reynoldsburg, OH USA

来源：

EMERGING INFECTIOUS DISEASES | 2014年 / 20卷 / 04期

关键词：

TRANSMISSIBLE GASTROENTERITIS VIRUS; RESPIRATORY CORONAVIRUS; UNITED-STATES; PIGLETS; SWINE; PREVALENCE; INFECTION; ENTERITIS;

D O I：

10.3201/eid2004.131685

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

To understand the progression of porcine epidemic diarrhea virus infection, we inoculated gnotobiotic pigs with a newly emerged US strain, PC21A, of the virus. At 24-48 hours postinoculation, the pigs exhibited severe diarrhea and vomiting, fecal shedding, viremia, and severe atrophic enteritis. These findings confirm that strain PC21A is highly enteropathogenic.

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收藏

页码：662 / 665

页数：4

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