Possible Role of Oxidative Stress in the Pathogenesis of Hypertension

被引：149

作者：

Ceriello, Antonio ^{[1
]}

机构：

[1] Univ Warwick, Clin Sci Res Inst, Warwick Med Sch, Ctr Excellence Diabet & Endocrinol,Univ Hosp Cove, Coventry CV2 2DX, W Midlands, England

来源：

DIABETES CARE | 2008年 / 31卷

关键词：

D O I：

10.2337/dc08-s245

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

Recently oxidative stress has been proposed as the cause of hypertension. An imbalance in superoxide and nitric oxide production may account for reduced vasodilation, which in turn can favor the development of hypetension. In vitro and in human studies support this hypothesis. The supplementation of antioxidants, particularly in the form of fresh fruit and vegetables, reduces blood pressure, supporting a role for free radicals in hypertension.

引用

收藏

页码：S181 / S184

页数：4

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