Emergence of Proteus mirabilis carrying the blaVIM-1 metallo-β-lactamase gene

被引:35
作者
Vourli, S.
Tsorlini, H.
Katsifa, H.
Polemis, M.
Tzouvelekis, L. S.
Kontodimou, A.
Vatopoulos, A. C.
机构
[1] Natl Sch Publ Hlth, Dept Microbiol, Athens 11521, Greece
[2] Gen Hosp G Papanikolaou, Microbiol Lab, Thessaloniki, Greece
[3] Univ Athens, Sch Med, Dept Microbiol, GR-11527 Athens, Greece
关键词
bla(VIM-1) gene; carbapenem resistance; integron; metallo-beta-lactamase; PCR mapping; Proteus mirabilis;
D O I
10.1111/j.1469-0691.2006.01489.x
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Seven genetically related Proteus mirabilis clinical isolates from a hospital in Thessaloniki, Greece, exhibited decreased susceptibility to imipenem and carried a bla(VIM-1) metallo-beta-lactamase gene. PCR mapping revealed that bla(VIM-1) was part of a class 1 integron that was probably located in the chromosome and also included the aacA7, dhfr and aadA genes. This is the first description of the bla(VIM-1) metallo-beta-lactamase gene in P. mirabilis.
引用
收藏
页码:691 / 694
页数:5
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