Evanescent microwaves: A novel super-resolution noncontact nondestructive imaging technique for biological applications

被引:71
作者
Tabib-Azar, M [1 ]
Katz, JL
LeClair, SR
机构
[1] Case Western Reserve Univ, Dept Elect Engn & Comp Sci, Cleveland, OH 44106 USA
[2] Case Western Reserve Univ, Dept Biomed Engn, Cleveland, OH 44106 USA
[3] USAF, Res Lab, Mat Mfg Directorate, Wright Patterson AFB, OH 45433 USA
关键词
biological materials; electromagnetic properties of materials; microwave imaging; material characterization; nearfield imaging; super-resolution imaging;
D O I
10.1109/19.816123
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
Scanning tunneling microscopes (STM) and atomic force microscopes (AFM) are used to study biological materials. These methods, often capable of achieving atomic resolutions, reveal fascinating information regarding the inner workings of these materials. However, both STM and AFM require physical contact to the specimen. In the case of STM the specimen needs to be conducting as well. Here we introduce a new method for imaging biological materials through air or a suitable liquid using decaying or evanescent fields at the tip of a properly designed microwave resonator. This novel method involves the use of an evanescent microwave probe (EMP) and it is capable of imaging a variety of nonuniformities in biological materials including conductivity, permittivity, and density variations. EMP is a noncontact and nondestructive sensor and it does not require conducting specimens. Its spatial resolution is currently around 0.4 mu m at 1 GHz, We have used this probe to map nonuniformities in a variety of materials including metals, semiconductors, insulators, and biological and botanical samples. Here we discuss applications of EMP imaging in bone, teeth, botanical, and agricultural specimens.
引用
收藏
页码:1111 / 1116
页数:6
相关论文
共 17 条
[1]   SUPER-RESOLUTION APERTURE SCANNING MICROSCOPE [J].
ASH, EA ;
NICHOLLS, G .
NATURE, 1972, 237 (5357) :510-&
[2]   Theory of diffraction by small holes [J].
Bethe, HA .
PHYSICAL REVIEW, 1944, 66 (7/8) :163-182
[3]   SCANNING ELECTROMAGNETIC TRANSMISSION-LINE MICROSCOPE WITH SUB-WAVELENGTH RESOLUTION [J].
FEE, M ;
CHU, S ;
HANSCH, TW .
OPTICS COMMUNICATIONS, 1989, 69 (3-4) :219-224
[4]  
GUTMANN RJ, 1987 IEEE MTT S DIG, P281
[5]   SCANNING ACOUSTIC MICROSCOPE STUDIES OF THE ELASTIC PROPERTIES OF OSTEONS AND OSTEON LAMALLAE [J].
KATZ, JL ;
MEUNIER, A .
JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 1993, 115 (04) :543-548
[6]  
KATZ JL, P 1998 IADR NIC FRAN
[7]  
KATZ JL, 1998, 20 ANN INT C IEEE EN
[8]  
KATZ JL, 1998, P 3 WORLD C BIOM AUG
[9]  
PATHAK P, 1998, P 1998 C NOND TEST A
[10]   MICROWAVE MAGNETIC MICROSCOPE [J].
SOOHOO, RF .
JOURNAL OF APPLIED PHYSICS, 1962, 33 (03) :1276-&