Adjuncts for ovarian stimulation: when do we adopt "orphan indications" for approved drugs?

被引：9

作者：

Meldrum, David R. ^{[1
]}

Chang, R. Jeffrey ^{[2
]}

de Ziegler, Dominique ^{[3
]}

Schoolcrcft, William B. ^{[4
]}

Scott, Richard T., Jr. ^{[5
]}

Pellicer, Antonio ^{[6
]}

机构：

[1] Reprod Partners Med Grp, Redondo Beach, CA 90277 USA

[2] Univ Calif San Diego, Dept Reprod Endocrinol & Infertil, San Diego, CA 92103 USA

[3] Univ Paris 05, Serv Gynecol Obstet & Med Reprod 2, CHU Cochin St Vincent Paul, Paris, France

[4] Colorado Ctr Reprod Med, Englewood, CO USA

[5] Reprod Med Associates New Jersey, Morristown, NJ USA

[6] Univ Valencia, Inst Valenciano Infertilidad, Valencia, Spain

来源：

FERTILITY AND STERILITY | 2009年 / 92卷 / 01期

关键词：

Ovarian stimulation; metformin; dexamethazone; hCG; aspirin; cabergoline; androgens; IN-VITRO FERTILIZATION; ENDOTHELIAL GROWTH-FACTOR; LOW-DOSE ASPIRIN; DEHYDROEPIANDROSTERONE-SULFATE LEVELS; OVULATION INDUCTION; DOUBLE-BLIND; TRANSDERMAL TESTOSTERONE; PITUITARY SUPPRESSION; CLOMIPHENE CITRATE; POOR-RESPONDERS;

D O I：

10.1016/j.fertnstert.2009.03.081

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Several drugs, shown to be safe for other uses, have proven to be highly effective adjuncts for ovarian stimulation. The authors evaluate these "orphan" indications and make recommendations so that more patients will benefit from their use. (Fertil Steril (R) 2009.92:13-8. (C)2009 by American Society for Reproductive Medicine.)

引用

页码：13 / 18

页数：6

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