Clinical review: A systematic review of corticosteroid use in infections

被引:16
作者
Aberdein, Jody [1 ]
Singer, Mervyn [1 ]
机构
[1] UCL Hosp NHS Trust, Dept Intens Care Med, London W1T 3AA, England
关键词
D O I
10.1186/cc3904
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Traditional teaching suggests that corticosteroids should be avoided during acute infectious episodes for fear of compromising the immune response. However, the outcome benefit shown through steroid administration in early septic shock implies this paranoia may be misplaced. We therefore performed a systematic review of the literature to identify the current strength of evidence for the use of corticosteroids in specified infections, and to make appropriate graded recommendations.
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页数:10
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