Endothelial dysfunction, inflammation and diabetes

被引:52
作者
Dandona, P [1 ]
Aljada, A [1 ]
Chaudhuri, A [1 ]
Mohanty, P [1 ]
机构
[1] SUNY Buffalo, Div Endocrinol Diabet & Metab, Buffalo, NY 14209 USA
关键词
inflammation; oxidative stress; NF-kappaB; insulin; obesity; type; 2; diabetes;
D O I
10.1023/B:REMD.0000032407.88070.0a
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
[No abstract available]
引用
收藏
页码:189 / 197
页数:9
相关论文
共 87 条
[1]   Insulin inhibits the pro-inflammatory transcription factor early growth response gene-1 (Egr)-1 expression in mononuclear cells (MNC) and reduces plasma tissue factor (TF) and plasminogen activator inhibitor-1 (PAI-1) concentrations [J].
Aljada, A ;
Ghanim, H ;
Mohanty, P ;
Kapur, N ;
Dandona, P .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2002, 87 (03) :1419-1422
[2]   Tumor necrosis factor-α inhibits insulin-induced increase in endothelial nitric oxide synthase and reduces insulin receptor content and phosphorylation in human aortic endothelial cells [J].
Aljada, A ;
Ghanim, H ;
Assian, E ;
Dandona, P .
METABOLISM-CLINICAL AND EXPERIMENTAL, 2002, 51 (04) :487-491
[3]   Nuclear factor-κB suppressive and inhibitor-κB stimulatory effects of troglitazone in obese patients with type 2 diabetes:: Evidence of an antiinflammatory action? [J].
Aljada, A ;
Garg, R ;
Ghanim, H ;
Mohanty, P ;
Hamouda, W ;
Assian, E ;
Dandona, P .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2001, 86 (07) :3250-3256
[4]  
Aljada A, 2001, DIABETES, V50, pA532
[5]  
ALJADA A, 2004, IN PRESS J CLIN ENDO
[6]   INHIBITION OF PLATELET-DERIVED MITOGEN RELEASE BY NITRIC-OXIDE (EDRF) [J].
BARRETT, ML ;
WILLIS, AL ;
VANE, JR .
AGENTS AND ACTIONS, 1989, 27 (3-4) :488-491
[7]   C-reactive-protein-associated increase in myocardial infarct size after ischemia/reperfusion [J].
Barrett, TD ;
Hennan, JK ;
Marks, RM ;
Lucchesi, BR .
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2002, 303 (03) :1007-1013
[8]   The relation of markers of inflammation to the development of glucose disorders in the elderly - The cardiovascular health study [J].
Barzilay, JI ;
Abraham, L ;
Heckbert, SR ;
Cushman, M ;
Kuller, LH ;
Resnick, HE ;
Tracy, RP .
DIABETES, 2001, 50 (10) :2384-2389
[9]   Tissue oxygenation and skin blood flow in the diabetic foot: Responses to cutaneous warming [J].
Boyko, EJ ;
Ahroni, JH ;
Stensel, VL .
FOOT & ANKLE INTERNATIONAL, 2001, 22 (09) :711-714
[10]   Microvascular and macrovascular reactivity is reduced in subjects at risk for type 2 diabetes [J].
Caballero, AE ;
Arora, S ;
Saouaf, R ;
Lim, SC ;
Smakowski, P ;
Park, JY ;
King, GL ;
LoGerfo, FW ;
Horton, ES ;
Veves, A .
DIABETES, 1999, 48 (09) :1856-1862