Stereoselective synthesis of the enantiomer of the key fragment of crocacin

被引：20

作者：

Raghavan, S ^{[1
]}

Reddy, SR ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Organ Div 1, Hyderabad 500007, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 29期

关键词：

crocacin; mercuric trifluoroacetate; Frater-alkylation;

D O I：

10.1016/j.tetlet.2004.05.130

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel, stereoselective synthesis of the enantiomer of alcohol 5 is disclosed. The key steps of the synthesis include mercuric trifluoroacetate promoted regio- and stereoselective hydration of an alpha,beta-unsaturated ester, Frater-alkylation and use Of morpholine derived amide for acylation. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：5593 / 5595

页数：3

共 20 条

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