Active synthesis of mouse polymeric immunoglobulin receptor in the epithelial cells of the distal urinary tubule in kidney

被引：13

作者：

Asano, M

Saito, M

Suguro, H

Nomura, H

Inage, T

Moro, I

机构：

[1] Nihon Univ, Sch Dent, Dept Pathol, Chiyoda Ku, Tokyo 1018310, Japan

[2] Nihon Univ, Sch Dent, Dept Endodont, Chiyoda Ku, Tokyo 1018310, Japan

[3] Nihon Univ, Sch Dent, Dept Anat, Chiyoda Ku, Tokyo 1018310, Japan

来源：

SCANDINAVIAN JOURNAL OF IMMUNOLOGY | 2004年 / 60卷 / 03期

关键词：

D O I：

10.1111/j.0300-9475.2004.01456.x

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 [免疫学];

摘要：

The tissue distribution of mouse polymeric immunoglobulin receptor (pIgR) has been demonstrated. By Northern blot hybridization, pIgR mRNA expression was detected in liver, intestine, stomach, lung and kidney. A weak expression was also detected in thymus by reverse transcriptase-polymerase chain reaction. The pIgR expression in kidney was further studied and confirmed that pIgR protein was actively synthesized in the epithelial cells of distal urinary tubule and of Henle's loop. Immunoelectron microscopical analysis showed the accumulation of pIgR-containing vesicles in the apical portion of distal urinary tubule epithelial cells.

引用

页码：267 / 272

页数：6

共 27 条

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