Minibrain (MNBH) is a single copy gene mapping to human chromosome 21q22.2

被引：4

作者：

Guimera, J ^{[1
]}

Pritchard, M ^{[1
]}

Nadal, M ^{[1
]}

Estivill, X ^{[1
]}

机构：

[1] LHOSP LLOBREGAT,INST CANC RES,DEPT MOL GENET,BARCELONA 08907,CATALONIA,SPAIN

来源：

CYTOGENETICS AND CELL GENETICS | 1997年 / 77卷 / 3-4期

关键词：

D O I：

10.1159/000134571

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

We have identified a human homologue of the Drosophila mnb gene (MNBH) on chromosome 21, while another study mapped an EST clone (R38268) with similarity to minibrain to human chromosome 1. This report describes the mapping of MNBH to a single locus on human chromosome 21q22.2 by FISH and Southern blotting. Comparison of the similarities between the two sequences and mnb demonstrates that MNBH on chromosome 21 is the true human homologue of Drosophila mnb.

引用

页码：182 / 184

页数：3

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