Immunization of animals: from DNA to the dinner plate

被引：54

作者：

Babiuk, LA ^{[1
]}

van Drunen Littel-van den Hurk, S ^{[1
]}

Babiuk, SL ^{[1
]}

机构：

[1] Univ Saskatchewan, Vet Infect Dis Org, Saskatoon, SK S7N 5E3, Canada

来源：

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY | 1999年 / 72卷 / 1-2期

基金：

加拿大自然科学与工程研究理事会; 英国医学研究理事会;

关键词：

DNA immunization; veterinary vaccines; immunity;

D O I：

10.1016/S0165-2427(99)00132-4

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Recently, there has been a great deal of interest in polynucleotide vaccination also referred to as DNA vaccines or genetic immunization for inducing long-term immunity in various animals and humans. The main attraction of this technology is the possibility to induce a broad range of immune responses without the use of conventional adjuvants. To date, most of the studies (>500 reports) have focused on DNA vaccination in mice. The present report summarizes the limited number of trials that have used target animal species to not only test the immune responses but also correlate them to protection. (C) 1999 Elsevier Science B.V. All rights reserved.

引用

页码：189 / 202

页数：14

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