Probing the dynamics of prion diseases with amphotericin B

被引：24

作者：

Adjou, KT

Deslys, JP

Demaimay, R

Dormont, D

机构：

[1] Service de Neurovirologie, CEA/CRSSA, DSV/DRM, 92265 Fontenay aux Roses Cedex

来源：

TRENDS IN MICROBIOLOGY | 1997年 / 5卷 / 01期

关键词：

D O I：

10.1016/S0966-842X(97)81771-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Amphotericin B (AmB) is one of the rare drugs that affect the course of experimental prion diseases and modify the kinetics of abnormal prion protein accumulation in the central nervous system. Therefore, AmB could be used as a pharmacological tool to contribute to our understanding of the pathogenic mechanisms involved in these neurodegenerative disorders.

引用

页码：27 / 31

页数：5

共 31 条

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