Amphotericin B-resistant Aspergillus flavus infection successfully treated with caspofungin, a novel antifungal agent

被引：28

作者：

Koss, T

Bagheri, B

Zeana, C

Romagnoli, MF

Grossman, ME

机构：

[1] Columbia Presbyterian Med Ctr, Dept Dermatol, Oklahoma City, OK 73104 USA

[2] Columbia Presbyterian Med Ctr, Dept Med, Div Infect Dis, Oklahoma City, OK 73104 USA

来源：

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY | 2002年 / 46卷 / 06期

关键词：

D O I：

10.1067/mjd.2002.120627

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Invasive aspergillosis is uncommon in immunocompetent hosts but is the second most common opportunistic fungal infection in immunocompromised patients. There has been a dramatic increase in the incidence of life-threatening aspergillosis during the past 2 decades, and the morbidity and mortality of these infections despite antifungal therapy remain unacceptably high. We describe a patient kith amphotericin B-resistant Aspergillus flavus successfully treated with caspofungin, an agent belonging to a new class of antifungal drugs. Caspofungin shows great promise in the treatment of invasive aspergillosis.

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页码：945 / 947

页数：3

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