Streptococcus pneumoniae produces a second haemolysin that is distinct from pneumolysin

被引：10

作者：

Canvin, JR

Paton, JC

Boulnois, GJ

Andrew, PW

Mitchell, TJ

机构：

[1] UNIV LEICESTER,DEPT MICROBIOL & IMMUNOL,LEICESTER LE1 9HN,LEICS,ENGLAND

[2] LENS & CHILDRENS HOSP,ADELAIDE,SA 5006,AUSTRALIA

来源：

MICROBIAL PATHOGENESIS | 1997年 / 22卷 / 03期

基金：

英国医学研究理事会;

关键词：

haemolysin; beta-haemolysis; pneumolysin; pneumococcus;

D O I：

10.1006/mpat.1996.0098

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Pneumococci are described as alpha-haemolytic but under certain circumstances they produce zones of beta-haemolysis on blood-containing medium. This observation was investigated using wild type strains and a genetically-modified strain unable to produce the haemolytic toxin, pneumolysin. beta-haemolysis was produced by all pneumococci tested. It was-not inhibited by anti-pneumolysin antibody but could be inactivated by cholesterol. These data confirm that pneumococci elaborate a second haemolysin, distinct from pneumolysin. (C) 1997 Academic Press Limited.

引用

页码：129 / 132

页数：4

共 18 条

[1] REDUCED VIRULENCE OF A DEFINED PNEUMOLYSIN-NEGATIVE MUTANT OF STREPTOCOCCUS-PNEUMONIAE [J].