Metabolic mechanisms associated with antianginal therapy

被引：17

作者：

Lewandowski, ED

机构：

[1] Massachusetts Gen Hosp, Dept Radiol, Metab Res Lab, Charlestown, MA 02129 USA

[2] Harvard Univ, Sch Med, Boston, MA USA

来源：

CIRCULATION RESEARCH | 2000年 / 86卷 / 05期

关键词：

myocardial ischemia; fatty acids; mitochondria; glycolysis; metabolism;

D O I：

10.1161/01.RES.86.5.487

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：487 / 489

页数：3

共 27 条

[1] Glucose-insulin-potassium in acute myocardial infarction - The time has come for a large, prospective trial [J].

Apstein, CS ;

Taegtmeyer, H .

CIRCULATION, 1997, 96 (04) :1074-1077

[2]

BRODBIN P, 1968, J CLIN PRACT, V22, P395

[3] TRIMETAZIDINE - A NEW CONCEPT IN THE TREATMENT OF ANGINA - COMPARISON WITH PROPRANOLOL IN PATIENTS WITH STABLE ANGINA [J].

DETRY, JM ;

SELLIER, P ;

PENNAFORTE, S ;

COKKINOS, D ;

DARGIE, H ;

MATHES, P .

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1994, 37 (03) :279-288

[4]

GRIFFIN J, IN PRESS AM J PHYSL

[5] AMP-activated protein kinase: an ultrasensitive system for monitoring cellular energy charge [J].

Hardie, DG ;

Salt, IP ;

Hawley, SA ;

Davies, SP .

BIOCHEMICAL JOURNAL, 1999, 338 :717-722

[6] Fatty acid oxidation in the reperfused ischemic heart [J].

Kantor, PF ;

Dyck, JRB ;

Lopaschuk, GD .

AMERICAN JOURNAL OF THE MEDICAL SCIENCES, 1999, 318 (01) :3-14

[7] The antianginal drug trimetazidine shifts cardiac energy metabolism from fatty acid oxidation to glucose oxidation by inhibiting mitochondrial long-chain 3-ketoacyl coenzyme A thiolase [J].

Kantor, PF ;

Lucien, A ;

Kozak, R ;

Lopaschuk, GD .

CIRCULATION RESEARCH, 2000, 86 (05) :580-588

[8] Effect of trimetazidine on carnitine palmitoyltransferase-1 in the rat heart [J].

Kennedy, JA ;

Horowitz, JD .

CARDIOVASCULAR DRUGS AND THERAPY, 1998, 12 (04) :359-363

[9] Inhibition of carnitine palmitoyltransferase-1 in rat heart and liver by perhexiline and amiodarone [J].

Kennedy, JA ;

Unger, SA ;

Horowitz, JD .

BIOCHEMICAL PHARMACOLOGY, 1996, 52 (02) :273-280

[10] EFFECTS OF ISCHEMIA AND REPERFUSION ON PYRUVATE-DEHYDROGENASE ACTIVITY IN ISOLATED RAT HEARTS [J].

KOBAYASHI, K ;

NEELY, JR .

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 1983, 15 (06) :359-367

← 1 2 3 →